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Human TDP43 Protein
Cat.#:TD-P-1010
Size: 50ug
Protein Name: TDP43
Synonym: ALS10; TDP-43
Uniprot No.: Q13148
Expression System: E. Coli
Compound Identity: TDP43(e3)-his
Full Length or Truncated:Full length
Molecular Weight: 47.2kD
Form: freeze-dried powder
Storage: -80°C (as supplied)
Stability: ≤6 months
Purity: ≥85% estimated by SDS-PAGE
Supplied in: 1×PBS (pH 7.2)
Background
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
SDS-PAGE Validation
12 % SDS-PAGE![]() 1 2 | Lane Description Lane 1: Protein Marker Lane 2: TDP43(e3)-pET21 |