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人重组蛋白

Human TDP43 Protein


Cat.#:TD-P-1010

Size:                                         50ug
Protein Name:                     TDP43 
Synonym:                              ALS10; TDP-43
Uniprot No.:                    Q13148
Expression System:         E. Coli
Compound Identity:        TDP43(e3)-his 
Full Length or Truncated:Full length
Molecular Weight:           47.2kD
Form:                               freeze-dried powder
Storage:                            -80°C (as supplied)
Stability:                           ≤6 months
Purity:                               ≥85% estimated by SDS-PAGE
Supplied in:                           1×PBS (pH 7.2)

Background


HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]


SDS-PAGE Validation

12 %  SDS-PAGE
                1        2
Lane Description


Lane 1:  Protein Marker  

Lane 2:  TDP43(e3)-pET21







    
   


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